Yes, Diabetes Insipidus (DI) is a rare condition that affects the kidneys and causes excessive urination and thirst. It occurs when the body does not produce enough antidiuretic hormone (ADH), also known as vasopressin, which helps the kidneys regulate the amount of water in the body. This leads to the production of large volumes of diluted urine and can cause dehydration if not treated. Symptoms of DI may include excessive thirst, frequent urination, bedwetting, and dry skin. There are different types of DI, including central DI, which is caused by a problem with the pituitary gland, and nephrogenic DI, which is caused by a problem with the kidneys. Treatment for DI typically involves medications to replace or stimulate the production of ADH, as well as measures to prevent dehydration.